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Synthesis and evaluation of novel picolinic acid-based bispidine ligands and their metal complexes for the application in nuclear medicine

Rück, Katharina

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Abstract

Defeating cancer is one of the major challenges that humankind is facing today. To this end, nuclear medicine offers promising approaches including radiometal-based pharmaceuticals. The work presented in this thesis focused on the development of new ligand systems for application as metal-chelating units in radiopharmaceuticals. These novel ligands were evaluated in various non-radioactive and radioactive metal complexation studies concerning their potential application in nuclear medicine.

Document type: Dissertation
Supervisor: Comba, Prof. Dr. Peter
Date of thesis defense: 14 July 2017
Date Deposited: 17 Aug 2017 09:13
Date: 2017
Faculties / Institutes: Fakultät für Chemie und Geowissenschaften > Institute of Inorganic Chemistry
DDC-classification: 500 Natural sciences and mathematics
540 Chemistry and allied sciences
Uncontrolled Keywords: Ligand synthesis, Coordination chemistry, Nuclear medicine
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